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Open Access Nano Express

Synthesis and self-assembly behavior of a biodegradable and sustainable soybean oil-based copolymer nanomicelle

Lixia Bao12, Longchun Bian2, Mimi Zhao2, Jingxin Lei1 and Jiliang Wang2*

Author Affiliations

1 State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China

2 School of Chemical Science and Technology, Yunnan University, Kunming 650091, China

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Nanoscale Research Letters 2014, 9:391  doi:10.1186/1556-276X-9-391

Published: 12 August 2014

Abstract

Herein, we report a novel amphiphilic biodegradable and sustainable soybean oil-based copolymer (SBC) prepared by grafting hydrophilic and biocompatible hydroxyethyl acrylate (HEA) polymeric segments onto the natural hydrophobic soybean oil chains. FTIR, H1-NMR, and GPC measurements have been used to investigate the molecular structure of the obtained SBC macromolecules. Self-assembly behaviors of the prepared SBC in aqueous solution have also been extensively evaluated by fluorescence spectroscopy and transmission electron microscopy. The prepared SBC nanocarrier with the size range of 40 to 80 nm has a potential application in the biomedical field.

Keywords:
Soybean oil; Self-assembly; Nanomicelle; Biomaterials