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Open Access Nano Express

One-step synthesis of platinum nanoparticles loaded in alginate bubbles

Chih-Hui Yang1, Wei-Ting Wang12, Alexandru Mihai Grumezescu3, Keng-Shiang Huang2* and Yung-Sheng Lin4*

Author Affiliations

1 Department of Biological Science and Technology, I-Shou University, Kaohsiung 82445, Taiwan

2 The School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 82445, Taiwan

3 Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, Bucharest 060042, Romania

4 Department of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung 43302, Taiwan

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Nanoscale Research Letters 2014, 9:277  doi:10.1186/1556-276X-9-277

Published: 30 May 2014


Composite particles with multifunctions have been extensively utilized for various applications. Bubble particles can be applied for ultrasound-mediated imaging, drug delivery, absorbers, cell culture, etc. This study proposes a one-step strategy to obtain Pt nanoparticles loaded in alginate bubbles. A needle-based droplet formation was used to generate uniform alginate particles about 2 mm in diameter. The hydrolysis reaction of NaBH4 was utilized to produce gaseous hydrogen and then trapped within alginate particles to form bubbles. The Pt4+ mixed with alginate solution was dropped into the reservoir to react with reducing NaBH4 and hardening CaCl2 to form Pt nanoparticles-alginate composite bubbles. Results indicate that the size of bubbles decreases with the CaCl2 concentration (1% ~ 20%), and size of bubbles increases with the NaBH4 concentration (1 ~ 20 mM). The advantages for the present approach include low cost, easy operation, and effective production of Pt nanoparticles-alginate composite bubbles.

Platinum; Bubbles; Alginate; Nanoparticle