Microscopic appearance of the substantia nigra stained with H & E. Microarchitecture of midbrain section (×10) in rats 4 weeks post-exposure to different concentrations of ZALH (A), ZALL (B), ZAH (C), ZAL (D) and vehicle control (E). Substantia nigra (SN), with abundant of dopaminergic neurons well outline from the brain of the control rats (E). The brain of all the four treated groups of animals also displayed similar features after H & E stain and viewed at ×10 magnification. No changes were seen in the treated group that could be attributed to the effect of nanocomposite exposure.
Kura et al. Nanoscale Research Letters 2014 9:261 doi:10.1186/1556-276X-9-261