Figure 4.

Distribution of F-actin in normal human pancreatic beta cells and IPCs treated with sugar. A and B show confocal images obtained using phalloidin-rhodamine to visualize actin in normal human pancreatic beta cells and IPCs. A1 and B1 were treated with D-PBS, the cortical F-actin network of these cells were continuous and dense; A2 and B2 show the cells in high-sugar-stimulated medium after 30 min; A3 and B3 show the cells in high-sugar-stimulated medium after 1 h; A4 and B4 show the cells in low-sugar-stimulated medium after 30 min; A5 and B5 show the cells in low-sugar-stimulated medium after 1 h.