Table 5

Relative volumes of significantly altered protein spots isolated from lung samples of rats
Spot Control H-nano-SiO2 L-nano-SiO2 H-nano-Fe3O4 L-nano-Fe3O4 H-SWCNTs L-SWCNTs
1 0.103 ± 0.020 0.195 ± 0.019a 0.184 ± 0.012a 0.162 ± 0.016a 0.172 ± 0.014a 0.160 ± 0.026a 0.194 ± 0.033a
2 0.087 ± 0.020 0.024 ± 0.011a 0.012 ± 0.003a 0.027 ± 0.008a 0.039 ± 0.014a 0.020 ± 0.010a 0.026 ± 0.005a
3 0.330 ± 0.039 0.128 ± 0.021a 0.182 ± 0.030a 0.200 ± 0.038a 0.143 ± 0.016a 0.140 ± 0.015a 0.182 ± 0.059a
4 0.356 ± 0.049 0.203 ± 0.015a 0.215 ± 0.022a 0.226 ± 0.011a 0.231 ± 0.026a 0.201 ± 0.023a 0.208 ± 0.019a
5 0.014 ± 0.006 0.032 ± 0.008a 0.030 ± 0.006a 0.031 ± 0.005a 0.032 ± 0.004a 0.040 ± 0.005a 0.031 ± 0.003a
6 0.193 ± 0.030 0.405 ± 0.047a 0.382 ± 0.045a 0.404 ± 0.044a 0.400 ± 0.050a 0.434 ± 0.024a 0.400 ± 0.037a
7 0.036 ± 0.007 0.012 ± 0.001a 0.017 ± 0.003a 0.012 ± 0.002a 0.017 ± 0.001a 0.012 ± 0.002a 0.013 ± 0.003a
8 0.053 ± 0.020 0.151 ± 0.020a 0.136 ± 0.044a 0.146 ± 0.021a 0.137 ± 0.007a 0.140 ± 0.029a 0.140 ± 0.013a
9 0.038 ± 0.006 0.016 ± 0.004a 0.017 ± 0.003a 0.017 ± 0.003a 0.019 ± 0.007a 0.010 ± 0.008a 0.013 ± 0.007a
10 0.092 ± 0.028 0.257 ± 0.027a 0.245 ± 0.020a 0.228 ± 0.039a 0.219 ± 0.031a 0.264 ± 0.040a 0.214 ± 0.029a
11 0.098 ± 0.013 0.016 ± 0.004a 0.024 ± 0.006a 0.018 ± 0.003a 0.023 ± 0.003a 0.013 ± 0.004a 0.022 ± 0.004a
12 0.030 ± 0.003 0.189 ± 0.051a 0.158 ± 0.036a 0.186 ± 0.044a 0.132 ± 0.022a 0.196 ± 0.027a 0.160 ± 0.044a
13 0.153 ± 0.020 0.031 ± 0.018a 0.059 ± 0.020a 0.045 ± 0.021a 0.070 ± 0.029a 0.040 ± 0.029a 0.054 ± 0.029a
14 0.012 ± 0.003 0.038 ± 0.008a 0.031 ± 0.007a 0.049 ± 0.009a 0.032 ± 0.005a 0.043 ± 0.009a 0.037 ± 0.007a
15 0.051 ± 0.008 0.135 ± 0.027a 0.109 ± 0.018a 0.126 ± 0.013a 0.122 ± 0.024a 0.147 ± 0.022a 0.114 ± 0.017a
16 0.021 ± 0.003 0.055 ± 0.007a 0.051 ± 0.012a 0.053 ± 0.011a 0.490 ± 0.007a 0.046 ± 0.008a 0.042 ± 0.004a
17 0.036 ± 0.009 0.088 ± 0.015a 0.079 ± 0.013a 0.105 ± 0.009a 0.0105 ± 0.025a 0.102 ± 0.030a 0.108 ± 0.015a

The rats were exposed to three types of nanomaterials: SiO2, Fe3O4, and SWCNTs. All the 17 spots have higher expression in the groups exposed to the three nanomaterials than in the control group (p < 0.05), and there is no significant difference between two doses of the same nanomaterial (p > 0.05). aCompared with the control group, p < 0.05.

Lin et al.

Lin et al. Nanoscale Research Letters 2013 8:521   doi:10.1186/1556-276X-8-521

Open Data