2-DE maps of lung proteins. From rats of the (A) control and (B-G) nanomaterial-treated groups (B, 2 mg/kg nano-Fe3O4; C, 2 mg/kg nano-SiO2; D, 2 mg/kg SWCNTs; E, 10 mg/kg nano-Fe3O4; F, 10 mg/kg nano-SiO2; G, 10 mg/kg SWCNTs). (H) Protein solutions from the lungs of male and female rats were separated by IEF (linear pH gradient from pH 3 to 10) and SDS-PAGE (13% polyacrylamide gel) methods, respectively . Each gel is representative of three independent replicates. There are 17 differentially expressed proteins from the rat lung, each marked by an arrow and number. The match rate of protein is over 72.2% among the samples at the same group.
Lin et al. Nanoscale Research Letters 2013 8:521 doi:10.1186/1556-276X-8-521