Large current difference in Au-coated vertical silicon nanowire electrode array with functionalization of peptides
1 Department of Materials Science and Engineering, Yonsei University, Seoul 120-749, Republic of Korea
2 Department of Physics, Chonbuk National University, Jeonju 561-756, Republic of Korea
Nanoscale Research Letters 2013, 8:502 doi:10.1186/1556-276X-8-502Published: 26 November 2013
Au-coated vertical silicon nanowire electrode array (VSNEA) was fabricated using a combination of bottom-up and top-down approaches by chemical vapor deposition and complementary metal-oxide-semiconductor process for biomolecule sensing. To verify the feasibility for the detection of biomolecules, Au-coated VSNEA was functionalized using peptides having a fluorescent probe. Cyclic voltammograms of the peptide-functionalized Au-coated VSNEA show a steady-state electrochemical current behavior. Because of the critically small dimension and vertically aligned nature of VSNEA, the current density of Au-coated VSNEA was dramatically higher than that of Au film electrodes. Au-coated VSNEA further showed a large current difference with and without peptides that was nine times more than that of Au film electrodes. These results indicate that Au-coated VSENA is highly effective device to detect peptides compared to conventional thin-film electrodes. Au-coated VSNEA can also be used as a divergent biosensor platform in many applications.