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Large current difference in Au-coated vertical silicon nanowire electrode array with functionalization of peptides

Ilsoo Kim1, So-Eun Kim1, Sanghun Han1, Hyungsuk Kim1, Jaehyung Lee1, Du-Won Jeong2, Ju-Jin Kim2, Yong-beom Lim1* and Heon-Jin Choi1*

Author Affiliations

1 Department of Materials Science and Engineering, Yonsei University, Seoul 120-749, Republic of Korea

2 Department of Physics, Chonbuk National University, Jeonju 561-756, Republic of Korea

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Nanoscale Research Letters 2013, 8:502  doi:10.1186/1556-276X-8-502

Published: 26 November 2013

Abstract

Au-coated vertical silicon nanowire electrode array (VSNEA) was fabricated using a combination of bottom-up and top-down approaches by chemical vapor deposition and complementary metal-oxide-semiconductor process for biomolecule sensing. To verify the feasibility for the detection of biomolecules, Au-coated VSNEA was functionalized using peptides having a fluorescent probe. Cyclic voltammograms of the peptide-functionalized Au-coated VSNEA show a steady-state electrochemical current behavior. Because of the critically small dimension and vertically aligned nature of VSNEA, the current density of Au-coated VSNEA was dramatically higher than that of Au film electrodes. Au-coated VSNEA further showed a large current difference with and without peptides that was nine times more than that of Au film electrodes. These results indicate that Au-coated VSENA is highly effective device to detect peptides compared to conventional thin-film electrodes. Au-coated VSNEA can also be used as a divergent biosensor platform in many applications.

Keywords:
Nanoelectrode; Silicon nanowire; Biomolecule sensing; Cyclic voltammograms; High current density