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A facile approach to synthesize SiO2 · Re2O3 (Re = Y, Eu, La, Sm, Tb, Pr) hollow sphere and its application in drug release

Zhihua Li1*, Lin Zhu1, Qian Liu1, Yu Du1 and Feng Wang2

Author affiliations

1 Department of Chemistry, College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China

2 College of Rizhao Polytechnic, Rizhao 276826, China

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Citation and License

Nanoscale Research Letters 2013, 8:435  doi:10.1186/1556-276X-8-435

Published: 21 October 2013


Multifunctional SiO2 · Re2O3 (Re = Y, Eu, La, Sm, Tb, Pr) hollow spheres (HSs) have been fabricated using an acidic Re3+ ion solution. Under ultraviolet radiation, functional HSs emit different colors of light according to the different rare-earth ions embedded into the shell of SiO2 hollow spheres. The as-prepared hollow capsules were characterized by X-ray diffraction, transmission electron microscopy, high-resolution transmission electron microscopy, Brunauer-Emmett-Teller method, scanning electron microscopy, and energy-dispersive spectrometry. Drug loading and release experiments have been carried out using SiO2 · Eu2O3 HSs that acted as drug carriers. The results demonstrate that the multifunctional HSs exhibit a high storage capacity and the ability of retaining drug stability and activity, which indicates that the as-synthesized fluorescent hollow capsules are a potential candidate as drug delivery materials.

SiO2 · Re2O3; Hollow spheres (HSs); Fluorescence