Table 2

Initial heating rates of uncoated and lipid-coated SPIONs following exposure to an alternating magnetic field
Particle concentration/suspension vehicle Initial heating rate (°C/min)
MFG-1000 at 7.0 mT (1 MHz) MHS at 16.6 mT (13.6 MHz)
Uncoated SPIONs Lipid-coated SPIONs Uncoated SPIONs Lipid-coated SPIONs
1 mg/mL (Citrate buffer) 0.88 ± 0.02 1.26 ± 0.03** 0.35 ± 0.01 0.61 ± 0.02**
0.24 mg/mL (Citrate buffer) 0.90 ± 0.02 1.05 ± 0.04 0.36 ± 0.02 0.56 ± 0.01
0.02 mg/mL (Citrate buffer) 0.95 ± 0.03* 0.94 ± 0.02 0.47 ± 0.01* 0.46 ± 0.01
0.02 mg/mL (HBSS) 0.66 ± 0.02 0.94 ± 0.01 0.33 ± 0.01 0.44 ± 0.02
0.02 mg/mL (PBS) 0.55 ± 0.02 0.92 ± 0.02 0.20 ± 0.01 0.43 ± 0.01

Data are shown as mean ± SD (n = 3).

*Significantly different from uncoated control SPIONs at 0.02 mg/mL (p < 0.05).

**Significantly different from lipid-coated SPIONs at 0.02 mg/mL in citrate buffer (p < 0.05).

Allam et al.

Allam et al. Nanoscale Research Letters 2013 8:426   doi:10.1186/1556-276X-8-426

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