Additional file 2: Figure S2.

(A) Histological analysis of kidney tissues in intraperitoneally administered mice. Vehicle or test article (snPt1 or snPt8 at 10 mg/kg) was administered intraperitoneally to mice as a single dose. At 24 h after administration, kidneys were collected and fixed with 4% paraformaldehyde. Tissue sections were stained with hematoxylin and eosin and observed under a microscope. (B) Acute kidney injury score in mice treated intraperitoneally with vehicle, snPt1, or snPt8. Grade 0: none, 1: slight, 2: mild, 3: moderate, 4: severe.

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Yamagishi et al. Nanoscale Research Letters 2013 8:395   doi:10.1186/1556-276X-8-395