Properties of silver nanostructure-coated PTFE and its biocompatibility
1 Department of Solid State Engineering, Institute of Chemical Technology, Prague 166 28, Czech Republic
2 Faculty of Science, J.E. Purkyně University, Usti nad Labem 400 96, Czech Republic
Nanoscale Research Letters 2013, 8:388 doi:10.1186/1556-276X-8-388Published: 17 September 2013
Silver nanolayers were sputtered on polytetrafluoroethylene (PTFE) and subsequently transformed into discrete nanoislands by thermal annealing. The Ag/PTFE composites prepared under different conditions were characterized by several complementary methods (goniometry, UV-visible spectroscopy, X-ray photoelectron spectroscopy, and atomic force microscopy), and new data on the mechanism of Ag layer growth and Ag atom clustering under annealing were obtained. Biocompatibility of selected Ag/PTFE composites was studied in vitro using vascular smooth muscle cell (VSMC) cultures. Despite of the well-known inhibitory properties of silver nanostructures towards broad spectrum of bacterial strains and cells, it was found that very thin silver coating stimulates both adhesion and proliferation of VSMCs.