Filopodial width distribution, p values, and diagram of CD4 cells bound on four QNPA substrates. (a) Filopodial width distribution of CD4 cells bound on the four different STR-functionalized QNPA substrates after only 20 min of incubation at 4°C. Selected filopodia with distribution (top part of figure) in which only approximately 80% of filopodial width taken from the results (bottom part of figure). (b) Summary of p values for filopodial width distribution of captured CD4 T cells on four different QNPA substrates. p values <0.0001 (****) are considered statistically significant. Less significant statistical difference is represented (* p = 0.0448). (c) Schematic diagram of CD4 T cell spreading mechanism just for 20 min of incubation.
Kim et al. Nanoscale Research Letters 2013 8:332 doi:10.1186/1556-276X-8-332