Table 1

Sequence alignment between Kv1.3, NavAb, and Nav1.8
Sequence alignment
Kv1.3 V V T M T T V G Y G D Ma
NavAb F Q V M T L Eb S W S Ma G
Nav1.8 I F R L M T Q Db S W E R La
Nav1.8 II F R I L C G Eb W I E N Ma
Nav1.8 III L Q V A T F Kb G W M D Ia
Nav1.8 IV F Q I T T S Ab G W D G La

Kv1.3 and NavAb are homotetramers, and Nav1.8 is a heterotetramer. bHomologues to Glu177. aPossible homologues to Met181.

Hilder and Chung

Hilder and Chung Nanoscale Research Letters 2013 8:323   doi:10.1186/1556-276X-8-323

Open Data