SGC-7901 cells were treated with 30 μg/mL etoposide in two forms of ECCNSs (f, g, and h) and void etoposide (b, c, and d). As the plots show, the number of events (y-axis) with high fluorescence intensity (x-axis) increases by 4-h incubation with ECCNSs but without any evident change for void etoposide. Negative control (a and e) includes nontreated cells to set their auto-fluorescence as ‘0’ value.
Peng et al. Nanoscale Research Letters 2013 8:321 doi:10.1186/1556-276X-8-321