Table 5

Effects of carbon dots on T lymphocyte subsets in spleen of BALB/c mice
Groups CD4+ (%) CD8+ (%) CD4+/CD8+
Saline 10.85 ± 1.15 5.47 ± 0.62 1.99 ± 0.17
Carbon dots
2 mg/kg 16.05 ± 0.24**↑ 9.89 ± 0.40**↑ 1.63 ± 0.09*↓
10 mg/kg 15.77 ± 0.59**↑ 9.16 ± 0.28**↑ 1.73 ± 0.12
50 mg/kg 16.56 ± 0.28**↑ 9.65 ± 0.44**↑ 1.72 ± 0.05

The effects were recorded 9 days after administration. The data are presented as mean ± standard deviations, n = 5. *P < 0.05 and **P < 0.01 compared with the saline group (control). Significant difference was calculated by one-way ANOVA using SPSS19.0.

Gao et al.

Gao et al. Nanoscale Research Letters 2013 8:276   doi:10.1186/1556-276X-8-276

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