Table 3

Effects of carbon dots on T lymphocyte subsets in spleen of BALB/c mice
Groups CD4+ (%) CD8+ (%) CD4+/CD8+
Saline 25.97 ± 0.65 9.94 ± 1.01 2.63 ± 0.21
Carbon dots
2 mg/kg 24.95 ± 0.20 12.54 ± 0.26**↑ 1.99 ± 0.04**↓
10 mg/kg 24.31 ± 0.41**↓ 11.00 ± 0.14 2.21 ± 0.05**↓
50 mg/kg 26.51 ± 0.44 12.75 ± 0.12**↑ 2.08 ± 0.04**↓

The effects were recorded 1 day after administration. Data are presented as mean ± standard deviations, n = 5. **P < 0.01 compared with the saline group (control). Significant difference was calculated by one-way ANOVA using SPSS19.0.

Gao et al.

Gao et al. Nanoscale Research Letters 2013 8:276   doi:10.1186/1556-276X-8-276

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