Table 4

The inhibition rate of GEM-ANPs on tumor growth in the PANC-1-induced nude mice tumor model
Group Tumor volume (mm3) Volume change, ΔV (mm3) Inhibitory rate of volumea (%) Tumor weightb (g) Inhibitory rate of weightc (%)
5 days 35 days
110-nm GEM-ANPs 144.9 ± 12.2 187.3 ± 32.4 42.4 75.1 0.175 39.9
406-nm GEM-ANPs 148.2 ± 10.4 31.0 ± 16.1 −117.2 168.8* 0.090* 69.1*
Gemcitabine 149.64 ± 20.35 132.80 ± 28.2 −16.8 109.9 0.166 43.0
ANPs 147.6 ± 22.7 250.6 ± 27.2 103.0 39.6 0.245 15.81
Control 149.4 ± 18.2 319.9 ± 30.3 170.5 0.0 0.291 0.0

n = 30. aInhibition rate of tumor volume = (Differences in mean tumor volume between the beginning and end of treatment group) / (differences in mean tumor volume between the begin and end of control group) × 100%. bThe tumor weight was measured at 35 days after administration. cInhibition rate of tumor weight = (Differences in mean tumor weight between treatment group and control group) / (Mean tumor weight of control group) × 100%. *Significant difference compared with gemcitabine group, p < 0.05.

Li et al.

Li et al. Nanoscale Research Letters 2013 8:176   doi:10.1186/1556-276X-8-176

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