SWNHs affected cell cycle of N9 cells, especially in pre-treated with LPS. Cell cycle of N9 cells was affected by SWNHs in a dose-dependent manner, especially in cells pre-treated with LPS (B). Followed with the increasing concentrations of SWNHs, the ratio of the G1 phase increased and S phase decreased significantly in N9 cells pre-treated with LPS (P < 0.01), the ratio of G2 phase decreased in N9 cells and it decreased until SWNHs30 and increased abruptly at the concentration of SWNHs40 in N9 cells pre-treated with LPS (P > 0.05). The effect induced by SWNHs on N9 cells pre-treated with LPS was more significant than on N9 cells. All data are represented as mean ± SEM.
Li et al. Nanoscale Research Letters 2013 8:100 doi:10.1186/1556-276X-8-100