Table 1

Characterization of sorafenib-incorporated nanoparticles

Polymer/drug

(mg/mg)

Drug contents (%, w/w)

Loading efficiency

(%, w/w)

Particle size

(nm)

Zeta potential

(mV)

Theoretical

Experimental


40:0

-

-

-

46 ± 1.12

-36.4 ± 3.1

40:2

4.76

1.23

25.84

63 ± 0.58

-35.5 ± 2.2

40:5

11.11

4.36

39.24

133 ± 0.58

-36.0 ± 1.1

40:7

14.89

5.26

35.33

181 ± 1.15

-35.8 ± 0.9


Kim et al. Nanoscale Research Letters 2012 7:91   doi:10.1186/1556-276X-7-91

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