Lipid peroxidation of SH-SY5Y and RAW 246.7 cells. LPO of the cells in response to MNP-PEI and MNP-PEI-PEG at 1.56 (white bar), 3.125 (light grey bar), 6.25 (grey bar), 12.5 (dark grey bar) and 25 μg mL-1 (black bar) over a period of 72 h. A1 LPO of SH-SY5Y cells in response to MNP-PEI, A2 LPO of RAW 246.7 cells in response to MNP-PEI, B1 LPO of SH-SY5Y cells in response to MNP-PEI-PEG and B2 LPO of RAW 246.7 cells in response to MNP-PEI-PEG. LPO values were calculated and expressed as nanomoles of MDA per milligram of cellular protein. (n = 3 ± SE.). Asterisk denotes significant increase compared to control cells (p, 0.05).
Hoskins et al. Nanoscale Research Letters 2012 7:77 doi:10.1186/1556-276X-7-77