Nano Commentary
Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilm development
1 ENT (Otolaryngology) Department, Coltea Hospital, Carol Davila University of Medicine and Pharmacy, IC Bratianu No. 1, Bucharest, 030171, Romania
2 Department of Microbiology, Faculty of Biology, Universtity of Bucharest, Aleea Portocalelor No. 1-3, Bucharest, 060101, Romania
3 Department of Science and Engineering of Oxidic Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, Polizu Street No. 1-7, Bucharest, 011061, Romania
4 ENT (Otolaryngology) Department, Coltea Hospital, Carol Davila University of Medicine and Pharmacy, IC Bratianu no 1, 030171, Bucharest, Romania
5 Center of Organic Chemistry “Costin D. Nenitescu”, Romanian Academy, 202B Splaiul Independentei, Bucharest, 050461, Romania
6 Doctor Anghel Medical Center, Theodor Sperantia Street, Bucharest, 30932, Romania
Nanoscale Research Letters 2012, 7:690 doi:10.1186/1556-276X-7-690
Published: 31 December 2012Abstract
This paper reports a newly fabricated nanophyto-modified wound dressing with microbicidal and anti-adherence properties. Nanofluid-based magnetite doped with eugenol or limonene was used to fabricate modified wound dressings. Nanostructure coated materials were characterized by TEM, XRD, and FT-IR. For the quantitative measurement of biofilm-embedded microbial cells, a culture-based method for viable cell count was used. The optimized textile dressing samples proved to be more resistant to staphylococcal and pseudomonal colonization and biofilm formation compared to the uncoated controls. The functionalized surfaces for wound dressing seems to be a very useful tool for the prevention of wound microbial contamination on viable tissues.



