Size distribution and enlarged SEM images of A549 cells. (a) Cell size and (b) nucleus size distribution (in μm2) of immobilized A549 cells on STR-functionalized three different substrates (planar glasses, QNP arrays, and SiNW arrays) after 0.5 to 45 h of incubation. (c) to (e) Top, tilled, and enlarged SEM images of A549 cells bound on SiNW arrays after 21 h of incubation at 37°C. The SiNW substrate was bent toward the center of the cells due to the high traction force these cells exerted (see arrows which indicate the bending direction).
Kim et al. Nanoscale Research Letters 2012 7:637 doi:10.1186/1556-276X-7-637