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Antibacterial performance of Ag nanoparticles and AgGO nanocomposites prepared via rapid microwave-assisted synthesis method

Soon Wei Chook1, Chin Hua Chia1*, Sarani Zakaria1, Mohd Khan Ayob2, Kah Leong Chee2, Nay Ming Huang3, Hui Min Neoh4, Hong Ngee Lim5, Rahman Jamal4 and RahaMohdFadhilRajaAbdul Rahman4

Author Affiliations

1 School of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, 43600, Malaysia

2 School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, 43600, Malaysia

3 Physics Department, Faculty of Science, University of Malaya, Kuala, Lumpur, 50603, Malaysia

4 UKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, 56000, Malaysia

5 Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor, 43400, Malaysia

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Nanoscale Research Letters 2012, 7:541  doi:10.1186/1556-276X-7-541

Published: 28 September 2012


Silver nanoparticles and silver-graphene oxide nanocomposites were fabricated using a rapid and green microwave irradiation synthesis method. Silver nanoparticles with narrow size distribution were formed under microwave irradiation for both samples. The silver nanoparticles were distributed randomly on the surface of graphene oxide. The Fourier transform infrared and thermogravimetry analysis results showed that the graphene oxide for the AgNP-graphene oxide (AgGO) sample was partially reduced during the in situ synthesis of silver nanoparticles. Both silver nanoparticles and AgGO nanocomposites exhibited stronger antibacterial properties against Gram-negative bacteria (Salmonella typhi and Escherichia coli) than against Gram-positive bacteria (Staphyloccocus aureus and Staphyloccocus epidermidis). The AgGO nanocomposites consisting of approximately 40 wt.% silver can achieve antibacterial performance comparable to that of neat silver nanoparticles.

Antibacterial properties; Graphene oxide; Microwave irradiation; Nanocomposites; Silver nanoparticles