Nano Express
Recognizing nucleosides with transverse electronic transport via perpendicular direction of base planes for DNA sequencing
Author affiliations
School of Physics Science and Information Technology, Liaocheng University, Liaocheng Shandong, 252059, China
Citation and License
Nanoscale Research Letters 2012, 7:512 doi:10.1186/1556-276X-7-512
Published: 19 September 2012Abstract
Putting the four DNA nucleosides in the middle of gold [111] nanoelectrodes with base planes parallel to the electrode surface layer, we study the transverse electronic transport properties of four nucleosides along the direction of electrodes. First, the optimal distance of the electrodes is released. The results show that the optimal electrode distance to study transverse electronic transport characteristics of DNA nucleosides is about 0.68 nm. Second, we theoretically calculate the conductance and current of the four nucleosides via perpendicular direction of base planes in the bias range of [−2, 2] V by exploiting the first principle theory. According to the calculated results, we propose three methods to recognize the nucleoside type in practice application.
