Table 1

Physical properties of liposomes
Liposome formulation Mean particle diameter Zeta potential DOX-Encapsulation efficiency Amount of Gd(III)
(molar ratio of lipids)
(nm) (mV) (%) (mM)
GdSL1 157.1 ± 8.9 −27.6 ± 4.2 46.6 ± 12.7 4.60 ± 0.16
Gd(III)-DOTA-DSPE/CHOL/DSPE-mPEG2000 = 31:15:4)
GdSL2 156.4 ± 5.1 −21.9 ± 1.0 41.7 ± 9.7 3.17 ± 0.01
Gd(III)-DOTA-DSPE/CHOL/DSPE-mPEG2000/DSPE = 20:15:4:11)
GdSL3 131.4 ± 9.1 −31.6 ± 7.2 62.9 ± 1.5 2.01 ± 0.31
Gd(III)-DOTA-DSPE/CHOL/DSPE-mPEG2000/DSPE = 10:15:4:21)
SL 129.1 ± 6.6 −31.9 ± 2.3 97.5 ± 0.4 ND
(CHOL/DSPE-mPEG2000/DSPE = 15:4:31)

ND, not detected (amount of Gd(III) could not be measured because there is no Gd(III)).

Jung et al.

Jung et al. Nanoscale Research Letters 2012 7:462   doi:10.1186/1556-276X-7-462

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