Figure 1.

Response surface plots of mean particle size (Y1) and entrapment efficiency (Y2) versus three factors. X₁ = duration of homogenization (min), X₂ = agitation speed (krpm), and X₃ = volume ratio of organic solvent phase to external aqueous phase (V/V). (A, B, C) The effect of duration of homogenization, agitation speed and volume ratio of organic solvent phase to external aqueous phase on the mean particle size. (D, E, F) The effect of duration of homogenization, agitation speed and volume ratio of organic solvent phase on the (EE)%.