Table 1
Pharmacokinetic parameters of DHA
Parameters	DHA N/O/W emulsion	DHA O/W emulsion	DHA solution
t1/2α (min)	9.40 ± 0.28*,**	3.97 ± 0.34	3.10 ± 0.09
t1/2β (min)	160.91 ± 47.21*,**	73.31 ± 1.61*	20.20 ± 6.56
Cl (ml·min−1·kg)	0.0023 ± 0.0002*,**	0.0038 ± 0.0002*	0.0069 ± 0.0013
AUC (min·ng·ml−1)	219,759.00 ± 14,782.77*,**	131,564.5 ± 8,396.89*	73,025.35 ± 14,149.00
MRT (min)	97.65 ± 20.27*,**	32.22 ± 4.03*	9.40 ± 2.44

Parameters of DHA after intravenous administration of DHA N/O/W emulsion to rabbits, DHA solution, and DHA O/W emulsion as controls. The results are expressed as mean ± S.D. (n = 6), *P < 0.01 vs. DHA solution, **P < 0.01 vs. DHA O/W emulsion.

Wang et al. Nanoscale Research Letters 2012 7:219   doi:10.1186/1556-276X-7-219