Prussian blue staining (A) and ICP-OES quantification of intracellular iron contents (B) of RAW267.4 cell incubated with SHU555A or MNCs with average size of 63 nm at the concentration of 10 μg/mL for different periods of time. Cell uptake of both iron oxide particles are time-dependent. However, cell incorporation of the MNCs are significantly higher than that of SHU555A. Bar: 20 μm.
Li et al. Nanoscale Research Letters 2012 7:204 doi:10.1186/1556-276X-7-204