Table 2

Results of sensitivity, specificity, PPV, and NPV of SPR array compared to ELISA assay results

Antigen numbera

Sensitivity (%)b

Specificity (%)b

PPV (%)b

NPV (%)b

SPR

ELISA

SPR

ELISA

SPR

ELISA

SPR

ELISA


W06

79

10

96

100

96

100

82

52

W10

45

38

100

96

100

92

64

60

W14

59

24

100

96

100

88

70

55

W19

31

62

96

79

90

75

57

67

W28

86

34

93

96

93

91

87

59

W38

79

24

100

100

100

100

82

56

W64

69

17

100

93

100

71

76

53

W70

14

24

100

100

100

100

53

56

W85

76

28

96

96

96

89

79

56

Multi-Ag

100

90

89

57

91

68

100

84


aA total of nine M. tuberculosis related antigens were used for the test. bResults shown were averages of three independent experiments. PPV, positive predictive value; NPV, negative predictive value; SPR, surface plasmon resonance; ELISA, enzyme-linked immunosorbent assay; Ag, antigen.

Hsieh et al. Nanoscale Research Letters 2012 7:180   doi:10.1186/1556-276X-7-180

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