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Encapsulation of docetaxel in oily core polyester nanocapsules intended for breast cancer therapy

Ibrahima Youm1, Xiaoyan Yang1, James B Murowchick2 and Bi-Botti C Youan1*

Author Affiliations

1 Laboratory of Future Nanomedicines and Theoretical Chronopharmaceutics, Division of Pharmaceutical Sciences, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO, 64108, USA

2 Department of Geosciences, University of Missouri-Kansas City, 420 Flarsheim Hall, 5110 Rockhill Rd., Kansas City, MO, 64110, USA

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Nanoscale Research Letters 2011, 6:630  doi:10.1186/1556-276X-6-630

Published: 14 December 2011

Additional files

Additional file 1:

Supplementary tables. Four supplementary tables showing the physicochemical characteristics of the Doc-loaded oily core nanocapsules (n = 3), key parameters resulting from fitting the Doc release profile to the Higuchi model, physicochemical properties of drug and excipients, and physicochemical properties and surface tension of drug and excipients, respectively.

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