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Trapping Iron Oxide into Hollow Gold Nanoparticles

Chienwen Huang1, Jiechao Jiang1, Chivarat Muangphat1, Xiankai Sun2 and Yaowu Hao1*

Author Affiliations

1 Department of Materials Science and Engineering, University of Texas at Arlington, Arlington, TX 76019, USA

2 Department of Radiology and Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA

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Nanoscale Res Lett 2011, 6:43  doi:10.1007/s11671-010-9792-x

Published: 28 September 2010


Synthesis of the core/shell-structured Fe3O4/Au nanoparticles by trapping Fe3O4 inside hollow Au nanoparticles is described. The produced composite nanoparticles are strongly magnetic with their surface plasmon resonance peaks in the near infrared region (wavelength from 700 to 800 nm), combining desirable magnetic and plasmonic properties into one nanoparticle. They are particularly suitable for in vivo diagnostic and therapeutic applications. The intact Au surface provides convenient anchorage sites for attachment of targeting molecules, and the particles can be activated by both near infrared lights and magnetic fields. As more and more hollow nanoparticles become available, this synthetic method would find general applications in the fabrication of core–shell multifunctional nanostructures.

Gold nanoparticles; Iron oxide nanoparticles; Core/shell nanoparticles; Hollow nanoparticles; Porous nanoparticles; Plasmonics