Table 3

IC50 of MCF-7 cells after 24-, 48-, 72-h incubation with docetaxel formulated in the Taxotere®, 5% DMAB-modified PLGA nanoparticles (ANP), unmodified PLGA-TPGS nanoparticles (BNP) and 5% DMAB-modified PLGA-TPGS nanoparticles (CNP)

Incubation time (h)

IC50(μg/ml)


ANP

BNP

CNP

Taxotere®


24

1.144

1.300

0.121

2.610

48

0.926

0.590

0.088

1.640

72

0.272

0.204

0.054

0.911


Chen et al. Nanoscale Res Lett 2011 6:4   doi:10.1007/s11671-010-9741-8

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