Table 1

Characterization of drug-loaded nanoparticles
Polymer Drug loading (%) Surfactant Size (nm) PDI ZP (mV) EE (%)
PLGA-TPGS 2.5 No 207.15 ± 8. 46 0.321 ± 0.03 58.87 ± 3.25
PLGA-TPGS 5 No 223.92 ± 6.27 0.372 ± 0.04 52.58 ± 2.94
PLGA-TPGS 10 No 244.71 ± 6.65 0.415 ± 0.02 −24.09 ± 1.45 48.35 ± 5.73
PLGA-TPGS 10 0.03% TPGS 265.43 ± 6.52 0.364 ± 0.03 −18.03 ± 1.89 99.31 ± 0.56
PLGA-TPGS 10 0.06% TPGS 290.25 ± 7.64 0.485 ± 0.01 −15.22 ± 2.12 85.85 ± 3.14
PLGA 10 0.03% TPGS 233.83 ± 9.62 0.293 ± 0.03 −32.10 ± 0.65 75.63 ± 3.42

* PDI Polydispersity Index, EE Drug encapsulation efficiency, n = 3

Ma et al.

Ma et al. Nanoscale Research Letters 2010 5:1161-1169   doi:10.1007/s11671-010-9620-3

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