Open Access Nano Express

The Photodynamic Effect of Different Size ZnO Nanoparticles on Cancer Cell Proliferation In Vitro

Jingyuan Li1, Dadong Guo1, Xuemei Wang1*, Huangping Wang1, Hui Jiang1 and Baoan Chen2

1 State Key Lab of Bioelectronics (Chien-Shiung WU Laboratory), Southeast University, 210096, Nanjing, People’s Republic of China

2 Department of Hematology, Zhongda Hospital, Southeast University, 210009, Nanjing, People’s Republic of China

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Nanoscale Research Letters 2010, 5:1063-1071 doi:10.1007/s11671-010-9603-4

Published: 16 April 2010

Additional files

Figure S1:

Figure S1 The TEM images of ZnO nanoparticles. (A) TEM image of the ZnO nanoparticle named ZP5 and (a) the corresponding HR-TEM image of the marked part A. (B) TEM image of the ZnO nanoparticle named ZP6 and (b) the corresponding HR-TEM image of the marked part B. (C) TEM image of the ZnO nanoparticle named ZP7 and (c) the corresponding HR-TEM image of the marked part C.

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Figure S2:

Figure S2 Dynamic response of SMMC-7721 cells exposure to ZP5 ZnO nanoparticles in the presence of UV irradiation for 180s: (a) ZnO nanoparticle-free (control); (b) 2.5 μg/mL of ZnO nanoparticles,(c) 5.0 μg/mL of ZnO nanoparticles, and (d) 10.0 μg/mL of ZnO nanoparticles.

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Figure S3:

Figure S3 Dynamic response of SMMC-7721 cells exposure to ZP6 ZnO nanoparticles in the presence of UV irradiation for 180s: (a) ZnO nanoparticle-free (control); (b) 2.5 μg/mL of ZnO nanoparticles,(c) 5.0 μg/mL of ZnO nanoparticles, and (d) 10.0 μg/mL of ZnO nanoparticles.

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Figure S4:

Figure S4 Dynamic response of SMMC-7721 cells exposure to ZP7 ZnO nanoparticles in the presence of UV irradiation for 180s: (a) ZnO nanoparticle-free (control); (b) 2.5 μg/mL of ZnO nanoparticles,(c) 5.0 μg/mL of ZnO nanoparticles, and (d) 10.0 μg/mL of ZnO nanoparticles.

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Figure S5:

Figure S5 Dynamic response of SMMC-7721 cells exposure to daunorubicin (1.0 ×10-7 mol/L) with ZP5 NPs. A: ZP 6 NPs and B: ZP 7 NPs. For A and B, a: negative control (ZnO nanoparticle-free); b: daunorubicin (1.0 ×10-7M); c: 2.5 μg/mL of ZnO NPs and daunorubicin (1.0 x 10-7M); and d: 5.0 μg/mL of ZnO NPs and daunorubicin (1.0 ×10-7M).

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