Open Access Nano Express

Coupling of Semiconductor Nanowires with Neurons and Their Interfacial Structure

Ki-Young Lee1, Sojung Shim1, Il-Soo Kim1, Hwangyou Oh1, Sunoh Kim2, Jae-Pyeong Ahn3, Seung-Han Park4, Hyewhon Rhim5* and Heon-Jin Choi1*

Author Affiliations

1 Department of Materials Science and Engineering, Yonsei University, Seoul, 120-749, South Korea

2 Jeonnam Natural Resources Research Institute, Jangheung-Gun, Jeollanamdo, 529-851, South Korea

3 Advanced Analysis Center, Korea Institute of Science and Technology, Seoul, 136-791, South Korea

4 Department of Physics, Yonsei University, Seoul, 120-749, South Korea

5 Center for Chemoinformatics Research, Korea Institute of Science and Technology, Seoul, 136-791, South Korea

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Nanoscale Research Letters 2009, 5:410-415  doi:10.1007/s11671-009-9498-0

Published: 4 December 2009

Abstract

We report on the compatibility of various nanowires with hippocampal neurons and the structural study of the neuron–nanowire interface. Si, Ge, SiGe, and GaN nanowires are compatible with hippocampal neurons due to their native oxide, but ZnO nanowires are toxic to neuron due to a release of Zn ion. The interfaces of fixed Si nanowire and hippocampal neuron, cross-sectional samples, were prepared by focused ion beam and observed by transmission electron microscopy. The results showed that the processes of neuron were adhered well on the nanowire without cleft.

Keywords:
Nanowires; Neurons; Coupling; Interfaces; TEM