Table 1 |
||
| Target oligonucleotide sequences | ||
| ssDNA | No. | Sequence (5′-3′) |
| 175wd | GGCACCCGCGTCCGCGCCATGGCCATCTAC | |
| 175G–A | 1 | GGCACCCGCGTCCCGCCATGGCCATCTAC |
| 245wd | TGCATGGGCGGCATGAACCGGAGGCCCATC | |
| 245G–T | 2 | TGCATGGGCGCATGAACCGGAGGCCCATC |
| 245G–A | 3 | TGCATGGGCGCATGAACCGGAGGCCCATC |
| 248wd | GCATGAACCGGAGGCCCATCCTCACCATCA | |
| 248G–A | 4 | GCATGAACCGAGGCCCATCCTCACCATCA |
| 248G–T | 5 | GCATGAACCGAGGCCCATCCTCACCATCA |
| 248C–T | 6 | GCATGAACGGAGGCCCATCCTCACCATCA |
| 249wd | GCATGAACCGGAGGCCCATCCTCACCATCA | |
| 249G1–T | 7 | GCATGAACCGGAGCCCATCCTCACCATCA |
| 249G2–T | 8 | GCATGAACCGGAGCCCATCCTCACCATCA |
| 249G-C | 9 | GCATGAACCGGAGCCCATCCTCACCATCA |
| 273wd | GAACAGCTTTGAGGTGCGTGTTTGTGCCTG | |
| 273G–T | 10 | GAACAGCTTTGAGGTGCTGTTTGTGCCTG |
| 273G–A | 11 | GAACAGCTTTGAGGTGCTGTTTGTGCCTG |
| 282wd | TCCTGGGAGAGACCGGCGCACAGAGGAAGA | |
| 282C–T | 12 | TCCTGGGAGAGACGGCGCACAGAGGAAGA |
The underline corresponds to the single base mismatch comparing with the wildtype (wd). 12 of the most frequent point mutations in exon 5, 7, and 8 of human p53 gene are included. 248wd and 249wd are the same sequences. The mutant sequences are numbered from 1 to 12
Sun et al. Nanoscale Research Letters 2008 4:216 doi:10.1186/1556-276X-4-216
