A periodic mesoporous organosilica (PMO) with nanorice morphology was successfully synthesized by a template assisted sol–gel method using a chain-type precursor. The PMO is composed of D and T sites in the ratio 1:2. The obtained mesoporous nanorice has a surface area of 753 m2 g−1, one-dimensional channels, and a narrow pore size distribution centered at 4.3 nm. The nanorice particles have a length of ca. 600 nm and width of ca. 200 nm.
Keywords:Nanorice; Mesoporous materials; Periodic mesoporous organosilica
Periodic mesoporous organosilicas (PMOs) have emerged as a diverse class of materials with numerous potential applications [1-3]. PMOs are attractive because they have a much higher and uniformly distributed loading of organic groups compared to organosilicas with post-grafted organic groups and organosilicas with terminal organic groups that have to be prepared by co-condensation methods [1-3]. Very little is known about the synthesis of PMO nanoparticles of controlled size and shape [4-7], and to our best knowledge there are no reports about uniform submicron PMO nanoparticles. Size and shape of mesoporous particles have a considerable impact on their potential uses. For example, periodic mesoporous silica nanoparticles of designed shapes have emerged as promising candidates for drug-delivery applications . Generally, it is difficult to achieve periodic mesoporous particles of uniform anisotropic shape and size, and special techniques are needed to produce them rationally and reproducibly [9-11]. Nanorices have been so far reported for dense nanoparticles, namely, iron oxide , organic polymers , silver , gold , and cobalt .
Herein, we report about the synthesis of periodic mesoporous organosilica nanorice from a novel chain-type precursor octaethoxy-1,3,5-trisilapentane1.In this precursor molecule two Si atoms are bound to one organic bridging group (T site) while one Si is bound to two organic bridging groups (D site). This structural motif DT2has not been used so far in PMO chemistry. Thus, the reported PMO has a novel composition and structure.
The nanorice was reproducibly obtained in a standard block copolymer template assisted sol–gel route  at room temperature without the need of any special reaction conditions.
Materials and Methods
Triblock copolymers EO20PO70EO20Pluronic P123 (BASF, USA), octaethoxy-1,3,5-trisilapentane (EtO)3Si–CH2–Si(OEt)2–CH2–Si(OEt)3(Gelest) and NaCl (EM Science) were used as-received without further purification.
Synthesis of PMO Nanorice
To a mixture of 6 g NaCl, 1.3 g of Pluronic 123, 32.4 mL (33.6 g) of 2 molar HCl and 11.2 mL H2O, 1.44 g of1was added drop wise under vigorous stirring. The mixture was continuously stirred for another 24 h under the formation of a suspension of a white solid. The solid particles were centrifuged off and re-suspended in a mixture of 100 mL acetone and 10 mL 2 molar HCl. This mixture was stirred for another 48 h to extract the template. The extracted particles were centrifuged again and dried at 80 °C for 1 h to yield 443 mg of final product.
Characterization of the Materials
The TEM images were taken on a JEOL JEM-2000 electron microscope operated at 200 kV. Samples for the TEM analysis were prepared by dispersing the particles in acetone and dropping a small volume of it onto a holey carbon film on a copper grid. SEM images of the specimen were taken on a Hitachi S-4300 SEM. SAXS patterns were obtained using a Rigaku Rotaflex diffractometer with a Cu Kαradiation source (λ = 0.15405 nm). The N2adsorption isotherm was measured at 77 K using an ASAP 2010 (Micromeritics Instrument Corp.). The free space He was determined prior to measuring the N2isotherm on a sample that was activated at 150 °C under dynamic vacuum to a vacuum of <10−5 Torr. After measuring the free space with He, the sample was again outgassed at 150 °C prior to measuring the N2isotherm. The BET surface area was calculated over the pressure range of 0.04–0.1 P/P0. The13C and29Si NMR spectra were obtained at 59.616 MHz (silicon-29) or 75.468 MHz (carbon-13) on a General Electric NMR Instruments model GN-300 equipped with a Doty Scientific 7 mm MAS probe. One pulse spectra were measured with a 1.0 μs pulse length (corresponding to a 20 degree tip angle) and a relaxation delay of 5.0 s (silicon) or 10 s (carbon) for 16,000 to 29,000 acquisitions while spinning at typically 5.0 kHz. Additional spectra (not shown) were acquired to assure quantitative NMR signal intensities. Proton decoupling during the 40 ms acquisition time was performed with a continuous 70 kHz radiofrequency field at 300.107 MHz. The time domain signal was conditioned with a Gaussian line-broadening function equivalent to 50 Hz prior to Fourier transformation.
Results and Discussion
The PMO nanorice particles have a narrow size distribution with an aspect ratio of ca. 3:1 (ca. 600 nm length, ca. 200 nm width) as seen by SEM and TEM (Fig. 1). The round ends and the relatively low aspect ratio make the nanorice structure clearly distinguished from nanorod type structures. TEM investigations further reveal a mesostructure with periodic one-dimensional channels with pore sizes of ca. 4 nm and channel wall diameters of ca. 6 nm. The mesochannels are highly aligned and run parallel to the largest particle dimension (Fig. 1d). Small angle powder-X-ray diffraction confirms the formation of a periodic mesostructure (Fig. 2). An intense reflex with an interplanar spacingd = 10.4 nm is observed corresponding to a lattice parametera = 12 nm.
13C MAS NMR (Fig. 3a) demonstrates the existence of organic groups in the framework. The signals around 5 ppm can be assigned to the CH2groups that bridge the Si tetrahedral centers. The absence of any further signals shows that the material is practically template free.29Si MAS NMR investigations (Fig. 3b) reveals that practically no Si–C bonds have cleaved during the synthesis and template removal process. The signals observed between −8 and −32 ppm can be assigned to D sites. The signals around −16 ppm represent D1sites, while signals around −24 ppm represent D2sites at the chain centre. The signals between −39 and −73 ppm can be assigned to T sites at the chain ends. The spectrum indicates the simultaneous presence of T1, T2, and T3sites at −48, −55, and −59 ppm, respectively.
Figure 3. a13C andb29Si MAS NMR spectra of PMO nanorice
The material shows a classical type IV isotherm with an N2hysteresis (Fig. 4a). The multipoint BET analysis reveals an N2surface area of 753 m2 g−1. The Gurvich volume of the sample at a P/P0of 0.97 was found to be 0.62 cc/g which is higher than the total pore volume from the desorption branch (0.51 cc/g). This phenomenon can be explained by interparticle void filling at high partial pressures. Calculation of the liquid N2pore volume at 350 cc/g (the plateau region) using the standard molar volumes for N2at 77 K gives a pore volume of 0.54 cc/g which is in good agreement with the total pore volume (0.51 cc/g) obtained from the desorption branch of the isotherm. From the desorption branch BJH analysis reveals a very narrow pore size distribution centered at 4.3 nm (Fig. 4b) which is in good agreement with the TEM data.
Figure 4. aN2sorption isotherm andbBJH pore size distribution of PMO nanorice
An interesting fact is that the aspect ratio of the obtained nanorice particles is close to the aspect ratio of the chain-type precursor and its hydrolyzed form (Fig. 5). This suggests that the hydrolyzed precursor may orient in a head-on manner with respect to the cylindrical micelles. Assuming equally fast polycondensation in all dimensions the particle grows anisotropically according to the aspect ratio of the precursor explaining the nanorice shaped particles.
Figure 5. Space-filling model of the energy-minimized hydrolyzed precursor (OH)3SiCH2Si(OH)2CH2Si(OH)3
In summary, we have synthesized a PMO with well-defined nanorice morphology. The particles are rather uniform and have a length of 600 nm and a width of 200 nm. A novel chain-type precusor with a DT2structural motif was used in the self-assembly process. The nanorice particles could be obtained in a surfactant templated self-assembly process without the need of a novel methodology or any other special aids.
We gratefully acknowledge the financial support from Lehigh University. We further thank Dr. Charles G. Coe and Michael F. Kimak for the N2gas sorption experiments. Dr. James E. Roberts is gratefully acknowledged for MAS NMR measurements. We further thank Dr. Chris Kiely and Dr. Dave Ackland for generously supporting our TEM investigations. Dr. G. Slade Cargill is gratefully acknowledged for supporting our X-ray diffraction experiments.
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