Figure 3.

Histopathology of the liver tissue (×100 or ×200) in female mice after intraperitoneal injection with various doses of nano-anatase TiO2suspensions for consecutive 14 days.aControl (×100): hepatocyte array is complete;b5 mg/kg BW nano-anatase TiO2(×100): hepatocyte is normal, sinus hepaticus is complete, vascellum is normal;c100 mg/kg BW nano-anatase TiO2(×100):Arrowsindicate congestion of vascellum and prominent vasodilatation;d150 mg/kg BW nano-anatase TiO2(×200):Arrowsindicate wide-bound basophilia;e150 mg/kg BW nano-anatase TiO2(×200):Arrowsindicate focal ischemia;f150 mg/kg BW bulk TiO2(×100):Arrowsindicate congestion of central veins

Ma et al. Nanoscale Research Letters 2009 4:1275-1285   doi:10.1007/s11671-009-9393-8