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Open Access Highly Accessed Nano Review

Magnetic Iron Oxide Nanoparticles: Synthesis and Surface Functionalization Strategies

Wei Wu1, Quanguo He2 and Changzhong Jiang1*

Author affiliations

1 Department of Physics, Wuhan University, Wuhan, 430072, People’s Republic of China

2 Key Laboratory of Green Packaging and Bio-Nanotechnology Applications (Hunan Province), Hunan University of Technology, Zhuzhou, 412008, People’s Republic of China

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Citation and License

Nanoscale Research Letters 2008, 3:397-415  doi:10.1007/s11671-008-9174-9

Published: 2 October 2008

Abstract

Surface functionalized magnetic iron oxide nanoparticles (NPs) are a kind of novel functional materials, which have been widely used in the biotechnology and catalysis. This review focuses on the recent development and various strategies in preparation, structure, and magnetic properties of naked and surface functionalized iron oxide NPs and their corresponding application briefly. In order to implement the practical application, the particles must have combined properties of high magnetic saturation, stability, biocompatibility, and interactive functions at the surface. Moreover, the surface of iron oxide NPs could be modified by organic materials or inorganic materials, such as polymers, biomolecules, silica, metals, etc. The problems and major challenges, along with the directions for the synthesis and surface functionalization of iron oxide NPs, are considered. Finally, some future trends and prospective in these research areas are also discussed.

Keywords:
Magnetic iron oxide NPs; Surface functionalization; Preparation; Application