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Combing and self-assembly phenomena in dry films of Taxol-stabilized microtubules

FabriceOlivier Morin1*, Franck Rose2, Pascal Martin3, Mehmet C Tarhan4, Hideki Kawakatsu1 and Hiroyuki Fujita1

Author Affiliations

1 LIMMS-CNRS/IIS, UMI 2820, University of Tokyo, 4-6-1 Komaba, Tokyo, 153-8505, Japan

2 Materials Sciences Division, L. Berkeley National Laboratory, One Cyclotron Road - Mailstop 66RO200, Building 66, Office 212, Lab 210, Berkeley, CA, 94720, USA

3 L2MP, Institut Supérieur d’Electronique et du Numérique Maison des Technologies, Pl. G. Pompidou, Toulon, 83000, France

4 IIS, University of Tokyo, 4-6-1 Komaba, Tokyo, 153-8505, Japan

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Nanoscale Research Letters 2007, 2:135-143  doi:10.1007/s11671-007-9044-x

The electronic version of this article is the complete one and can be found online at:

Received:13 December 2006
Accepted:4 February 2007
Published:13 March 2007

© 2007 to the authors


Microtubules are filamentous proteins that act as a substrate for the translocation of motor proteins. As such, they may be envisioned as a scaffold for the self-assembly of functional materials and devices. Physisorption, self-assembly and combing are here investigated as a potential prelude to microtubule-templated self-assembly. Dense films of self-assembled microtubules were successfully produced, as well as patterns of both dendritic and non-dendritic bundles of microtubules. They are presented in the present paper and the mechanism of their formation is discussed.

Adsorption; HOPG; Microtubules; Self-assembly

Nano Express


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Electronic Supplementary Material. The online version of this article (doi:10.1007/s11671-007-9044-x) contains supplementary material, which is available to authorized users.

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F.O.M. and F.R. acknowledge the financial support of the Japan Society for the Promotion of Science (JSPS). P.M. acknowledges the financial support of the Centre National de la Recherche Scientifique (CNRS). F.O.M. and M.C.T. acknowledge prof. S. Takeuchi for permitting the use of ultra-centrifuges.


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